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. 2019 Jan 31;10:7. doi: 10.3389/fgene.2019.00007

Table 2.

eQTL analysis: Significant associations from multivariate regression models after Bonferroni correction (only minimal p-values of four genetic models used are listed).

Gene Varianta dbSNP151 Functional class Minimal p-valueb
ABCA5 17_67242245_G_A rs12942867 3′UTR 1.20E-08 A
17_67242551_AG_A rs321469 3′UTR 1.20E-08 A
17_67242756_G_A rs1990248 3′UTR 9.00E-08 A
17_67243289_A_T rs15886 3′UTR 1.20E-08 A
17_67260926_A_G rs12449649 Synonymous 1.00E-08 A
17_67267317_T_C rs557491 Missense 1.10E-07 A
17_67282332_T_C rs1550828 Intron 1.00E-08 A
ABCC11 16_48250011_G_A rs11863233 Intron 6.90E-11 A
16_48250026_G_T rs11863236 Missense 6.90E-11 A
16_48250218_T_C rs28654935 Intron 6.90E-11 A
16_48256602_T_C rs16945974 Synonymous 6.90E-11 A
16_48265777_C_T rs16945988 Missense 6.90E-11 A
16_48269120_TAGAGATGCAA_T rs398088092 Upstream 3.20E-10 C
16_48269140_AAGAGATGCAA_A Upstream 1.80E-09 A
16_48269561_A_G rs10521167 Upstream 6.90E-11 A
16_48269918_T_C rs16946006 Upstream 6.90E-11 A
16_48270429_C_T rs9926206 Upstream 6.90E-11 A
16_48270508_T_C rs9934833 Upstream 6.90E-11 A
16_48270574_A_G rs9932328 Upstream 6.90E-11 A
AOC1 7_150553605_C_T rs10156191 Missense 8.50E-06 A
7_150555915_A_G rs10893 Synonymous 3.40E-08 R
7_150557622_G_A rs12179 Synonymous 6.50E-09 R
7_150557665_C_G rs1049793 Missense 6.50E-09 R
7_150558366_C_T rs12539 3′UTR 6.30E-09 D
ALDH6A1 14_74527190_A_G rs8204 3′UTR 1.40E-05 C
ARNT 1_150783934_G_GCACA rs71580328 3′UTR 1.90E-10 D
1_150783934_G_GCACACA rs71580328 3′UTR 5.80E-10 C
1_150783985_T_C rs11552229 3′UTR 3.10E-12 A
1_150804401_G_GA rs200891935 Intron 4.60E-10 C
1_150808889_C_G rs2228099 Synonymous 6.70E-12 A
1_150850904_CA_C rs10305645 Upstream 1.50E-11 D
ARSA 22_51062832_G_A rs8142033 3′UTR 9.10E-15 A
22_51063477_T_C rs6151429 3′UTR 3.70E-18 A
22_51064039_G_C rs743616 Missense 6.40E-07 A
22_51064416_T_C rs2071421 Missense 7.30E-12 A
CAV1 7_116200587_C_T rs1049337 3′UTR 2.50E-16 A
CYP2D6 22_42528382_C_G rs1080985 Upstream 2.40E-06 D
CYP2R1 11_14900931_G_A rs117913124 Synonymous 1.10E-05 D
CYP3A5 7_99245914_A_G rs15524 3′UTR 2.10E-13 D
CYP4F11 19_16023318_C_G rs61175303 3′UTR 3.10E-06 C
19_16023378_G_A rs58046343 3′UTR 3.10E-06 C
19_16023619_T_C rs58153611 3′UTR 3.10E-06 C
CYP4F12 19_15791132_T_A rs2074568 Intron 1.80E-09 A
19_15793235_T_C rs2285888 Missense 8.30E-06 A
19_15807884_A_G rs593818 Missense 1.80E-06 A
EPHX2 8_27373923_T_C rs4149243 Splice_region 2.20E-08 D
8_27396208_G_A rs4149253 Synonymous 5.80E-06 C
8_27401964_A_C rs1126452 Synonymous 3.60E-12 D
8_27402074_A_G rs1042032 3′UTR 3.60E-12 D
8_27402132_T_C rs1042064 3′UTR 1.20E-12 D
FMO4 1_171311003_A_C rs1042772 3′UTR 1.70E-06 A
GPX4 19_1106477_G_C rs8178977 Intron 1.80E-09 A
19_1106615_T_C rs713041 3′UTR 6.90E-06 A
GPX7 1_53074532_C_A rs1047635 3′UTR 2.50E-23 C
GSR 8_30535660_C_A rs3594 3′UTR 1.10E-15 A
8_30536581_A_G rs1138054 3′UTR 2.90E-07 A
GSTM2 1_110210780_C_G rs530021 Splice_region 6.10E-07 A
GSTO2 10_106034491_A_G rs2297235 5′UTR 1.00E-12 A
10_106037894_T_C rs157077 Intron 2.40E-08 A
GSTZ1 14_77788908_G_A rs2363643 Intron 1.40E-06 A
14_77793207_G_A rs7975 Missense 8.70E-06 A
NUDT8 11_67395714_C_T rs7124513 Synonymous 2.50E-07 A
PIAS2 18_44390536_T_C rs17472 3′UTR 3.50E-07 A
18_44391566_T_TAG rs149022619 3′UTR 3.50E-07 A
PON1 7_94927924_C_T rs854552 3′UTR 1.20E-06 A
7_94953895_G_A rs705379 Upstream 1.90E-09 A
SLC22A10 11_63057925_G_A rs1790218 Stop_gained 2.50E-21 C
11_63064823_T_C rs576641 Synonymous 5.10E-19 A
11_63072310_C_T rs1201559 Missense 2.50E-21 C
11_63078986_T_C rs1404608 3′UTR 2.50E-21 C
11_63079101_AT_A rs5792282 3′UTR 4.40E-20 A
SLC29A4 7_5338714_T_C rs6950111 Synonymous 8.20E-09 A
7_5342413_T_C rs11979775 Intron 4.10E-07 D
7_5342980_C_T rs56166050 3′UTR 2.80E-06 D
SQSTM1 5_179260153_C_T rs4935 Synonymous 1.40E-13 A
5_179260213_G_A rs4797 Synonymous 2.80E-13 A
5_179264731_T_C rs10277 3′UTR 7.60E-17 A
5_179264915_G_T rs1065154 3′UTR 1.30E-15 A
SULT2A1 19_48374306_G_A rs112468411 3′UTR 3.50E-10 C
19_48374320_C_T rs112285002 3′UTR 1.50E-61 C
19_48374538_T_C rs296366 3′UTR 1.90E-64 C
19_48374551_C_G rs296365 3′UTR 5.60E-21 R
19_48389363_G_A rs296361 Intron 3.30E-34 C
UGT2A1 4_70454289_A_G rs4148312 3′UTR 5.20E-08 A
UROC1 3_126200146_A_T rs777513 3′UTR 1.40E-10 A
3_126200291_C_T rs800950 3′UTR 7.70E-07 R
3_126200403_A_C rs1799398 3′UTR 3.10E-12 A
3_126202257_G_A rs1687477 Synonymous 8.50E-06 R
VKORC1 16_31102321_C_T rs7294 3′UTR 5.50E-07 A
XRCC5 2_217012901_A_G rs207906 Synonymous 7.60E-06 D

aVariant identifier “chromosome _ position _ reference nucleotide _ variant nucleotide”.bGenetic model with minimal p-value: A, additive; R, recessive; D, dominant; C, codominant.