Table 1.
Metabolites | VIPa | P-valueb | FC (REB/REW)c | KEGGd | Related pathway |
---|---|---|---|---|---|
Fructose | 1.68 | 0.045 | 1.17 | C02336 | Amino sugar and nucleotide sugar metabolism |
Lactic acid | 1.77 | 0.032 | 0.69 | C00186 | Glycolysis/ Gluconeogenesis; Fructose and mannose metabolism; Pyruvate metabolism |
D-pinitol | 1.68 | 0.044 | 0.52 | C03844 | — |
Sucrose | 1.86 | 0.022 | 1.12 | C00089 | Galactose metabolism; Starch and sucrose metabolism |
Threonine | 1.71 | 0.040 | 0.87 | C00188 | Glycine, serine and threonine metabolism; Valine, leucine and isoleucine biosynthesis |
Hexanoic acid | 2.04 | 0.009 | 0.39 | C01585 | Fatty acid |
aVIP values, Variable Importance in the Projection, was obtained from the OPLS-DA model. bP-value was calculated from a two-tailed Student’s t-test. cFC (REB/REW), fold change, was calculated as a binary logarithm of the average mass response (normalized peak area) ratio between Group REB vs. Group REW, where a positive value means that the average mass response of the metabolite in Group REB is larger than that in Group REW. dKEGG: Kyoto Encyclopedia of Genes and Genomes http://www.kegg.jp/.