Figure 6.

miR-103/107 Inhibition in Cardiomyocytes Affects Mitochondrial Morphology

(A) Maximum-intensity projections of nRCMs stained with calcein (green), Hoechst (blue), and TMRM (red) to visualize cytosol, nuclei, and mitochondria, respectively. Scale bar, 10 μm. (B) Mitochondrial network analyses including cell and mitochondria volume, mitochondrial intensities (reflecting mitochondrial membrane potential) as measured by TMRM fluorescence, and quantification of mitochondrial number and size. Scr, scrambled; ant, inhibitors. Data are presented as mean ± SEM of 40 individually analyzed cells per condition; *p < 0.05 versus scr.