. 2019 Feb 6;9:1455. doi: 10.1038/s41598-018-37828-5

Table 2.

The concentrations of glycolysis metabolites in erythrocytes, measured in various studies, as well as the steady-state concentrations of these metabolites obtained in the model (for normal physiological conditions)^a.

Metabolite	Range of the intracellular concentration measured experimentally, mmol/l_RBCs	Steady-state intracellular concentration calculated in model, mmol/l_RBCs	References
G6P	0.02–0.11	0.073	^{53, 54, 58– 64}
F6P	0.006–0.016	0.024	^{53, 54, 59– 63}
FDP	0.002–0.03	0.0075	^{53, 54, 58– 62, 64}
DAP	0.0076–0.035	0.032	^{53, 54, 61, 62, 65}
GAP	0.0048–0.02	0.014	^{59, 61, 63, 65}
1,3-DPG	(0.62–4.3) × 10⁻⁴	7.2 × 10⁻⁴	^61, 66
2,3-DPG	4.17–5.7	4.57	^{53, 54, 59– 61, 63– 65}
3-PG	0.055–0.069	0.045	^{53, 54, 59– 61, 63}
2-PG	0.0055–0.012	0.011	^{53, 54, 59– 61, 63}
PEP	0.012–0.018	0.0098	^{53, 54, 59– 61, 63}
NAD	0.032–0.092	0.048	^48, 67
NADH	0.001–0.054	0.002	^48, 67
PО₄	0.5–0.9	1	^53, 68, 69
ATP	1.07–1.8	1.47	^60– 62, 64
ADP	0.085–0.3	0.23	^60– 62, 64
AMP	0.01–0.05	0.04	^60– 62, 64
NADP	0.0003–0.023	0.0003	^48, 70– 72
NADPH	0.035–0.06	0.0498	^48, 70– 72
Na⁺ ions	9.2–12.6	10	^73, 74

^aFor abbreviations, see legend to Fig. 1.