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. 2019 Feb 6;9:1503. doi: 10.1038/s41598-018-38134-w

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Can f 6-specific IgE levels in sera of dog-allergic patients. Sera from 18 out of 38 (47%) dog-allergic patients show Can f 6-reactive IgE levels above the cut-off value (the mean of non-dog-allergic subjects +3× SD), as indicated by black bars. White bars indicate sera from 20 dog-allergic patients that show Can f 6-reactive IgE levels below the cut-off value. Sera from 6 non-allergic donors are indicated by N1 to N6 (grey bars). The data are expressed as the mean ± SD (n = 3).