Table 5. Effects of high and low sugars diets on palmitate kinetics, post-heparin lipase activities and plasma apoproteins.
NAFLD (n = 11) | Controls (n = 14) | |||
---|---|---|---|---|
High sugars | Low sugars | High sugars | Low sugars | |
Plasma NEFA (μmol/l) | 658 ± 301 | 548 ± 44 | 438 ± 31 | 526 ± 422 |
Plasma Palmitate (μmol/l) | 220 ± 39 | 238 ± 25 | 214 ± 25 | 218 ± 28 |
Palmitate production rate (μmol/min) | 169 ± 11 | 147 ± 123 | 168 ± 15 | 168 ± 17 |
Palmitate MCR (ml/min) | 863 ± 74 | 647 ± 564 | 863 ± 110 | 850 ± 101 |
Post heparin LPL (pmol/ml/min) | 1.33 ± 0.31 | 1.30 ± 0.21 | 1.36 ± 0.19 | 1.97 ± 0.32 |
Post heparin HL (pmol/ml/min) | 2.13 ± 0.482 | 1.43 ± 0.38 | 1.01 ± 0.17 | 0.90 ± 0.18 |
Plasma apoE (mg/l) | 33.3 ± 3.7 | 30.2 ± 2.7 | 29.1 ± 1.4 | 27.7 ± 1.4 |
Plasma apo C-III (mg/l) | 112.2 ± 9.82 | 103.8 ± 9.15 | 86.0 ± 7.5 | 73.5 ± 5.4 |
Plasma apo C-II (mg/l) | 82.7 ± 9.2 | 77.0 ± 8.02 | 61.7 ± 6.1 | 56.9 ± 5.6 |
Values are mean ± SEM. Significant difference between groups (within diet): 1P<0.001; 2P<0.05; 5P<0.01 Significant difference between diets (within group); 3P<0.05; 4P<0.01. All differences were adjusted for body weight.