Figure 8. Global PTP1B inhibition improves aortic AMPK signalling.

(A) Western blot analysis of aortic tissues from saline, single dose and chronic HFD cohorts injected with insulin immediately prior to culling. Quantification, p-AMPKα (Thr¹⁷²) (B) and p-p38 (Thr¹⁸⁰/Tyr¹⁸²) (C) using ImageJ software. Data are represented as mean ± S.E.M. and analysed by one-way ANOVA followed by Dunnett’s ttests where *P≤0.05 when compared with saline control.