Supplemental Figure 1.

Trodusquemine treatment reduces food intake. Food intake of HFD (A) and CHOW-fed (B) cohorts at week 9. PTP1B activity data of liver tissue from HFD-fed saline, single dose or chronically trodusquemine treated cohorts following terminal culls as assessed by inhibition of free phosphate production (C, n=4-5 per group). Data are represented as mean ± S.E.M. and analysed by unpaired two tailed t-tests where *p≤0.05 or ****p≤0.0001 when compared to saline control groups.

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