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. 2019 Feb 6;9:1530. doi: 10.1038/s41598-018-38383-9

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effects of DOSS treatment on adipose tissue mass and percent adipose tissue and male and female F1 mice. At 16 weeks of age, F1 males (n = 28 treatment, 30 control) and females (n = 16/group) were sacrificed and inguinal and gonadal adipose tissue was weighed and collected. Adipose tissue percent was calculated as the weight of adipose tissue/total body mass. Measurements were obtained for (A) male adipose tissue mass, (B) male adipose tissue percent, (C) female adipose tissue mass, and (D) female adipose tissue percent. Graph bars represent standard deviations. Unpaired students t-test with Welch’s correction for unequal variance was used for male mice (*p < 0.05).