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. 2019 Jan 31;12:13. doi: 10.3389/fnmol.2019.00013

Figure 1.

Figure 1

Effect of the Dicer knock-down on the inhibitory function of 3′-UTR sequence (A–D). When the endogenous Dicer enzyme of the four cell lines were knocked down, we found that the inhibition of the 3′-UTR sequence was not significant in SK-N-SH and U87 cells. The results indicated that the down-regulation of gene expression by the 3′-UTR sequence might be exerted by the Dicer-mediated miRNAs. **0.001 ≤ p < 0.02.