Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jan 11;41(3):1678–1690. doi: 10.3892/or.2019.6968

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 2. — SP cells express high levels of ABCG2 and display more potent chemoresistance than MP cells. (A) Ratios of ABCA3, ABCB1, ABCC1 and ABCG2 transcripts in SP NCI-H929 cells relative to MP NCI-H929 cells. (B) mRNA expression levels of ABCG2, as determined using DNA agarose gel electrophoresis. (C) ABCG2 protein expression levels were increased in SP cells compared with in MP cells. (D and E) Survival ratio of SP and MP cells treated with various doses of (D) Bort or (E) As₂O₃. **P<0.01. ABC, ATP binding cassette; ABCA3, ABC subfamily A member 3; ABCB1, ABC subfamily B member 1; ABCC1, ABC subfamily C member 1; ABCG2, ABC subfamily G member 2; As₂O₃, arsenic trioxide; Bort, bortezomib; MP, main population; SP, side population.