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. 2019 Jan 24;41(3):1549–1559. doi: 10.3892/or.2019.6983

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Copyright: © Ma et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — miRNA-223 affects EGFR, PI3K and p-Akt protein expression of A549 cells. (A) miRNA-223 binding site with EGFR. (B-D) EGFR, PI3K and p-Akt protein expression by statistical analysis and (E) western blot assays following downregulation of miRNA-223 expression. (F-H) EGFR, PI3K and p-Akt protein expression by statistical analysis and (I) western blot assays following upregulation of miRNA-223 expression. Control, control group; Anti-223, downregulated miRNA-223 expression group; miR-223, upregulated miRNA-223 expression group. ^##P<0.01 compared with the control group.