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. 2019 Jan 24;41(3):1549–1559. doi: 10.3892/or.2019.6983

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Copyright: © Ma et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 7. — Inhibition of EGFR increases the anticancer effects of miRNA-223 in A549 cells. (A) Cell proliferation, (B and C) migration rate. Control, control group; miR-223, upregulated miRNA-223 expression group; EGFR inhibitor, upregulated miRNA-223 expression and EGFR inhibitor group. ^##P<0.01 compared with the control group; **P<0.01 compared with the upregulated miRNA-223 expression group. Inhibition of EGFR increases the anticancer effects of miRNA-223 in A549 cells. (D and E) Apoptosis rate, (F) LDH activity, and (G) caspase-3/9 activity. Control, control group; miR-223, upregulated miRNA-223 expression group; EGFR inhibitor, upregulated miRNA-223 expression and EGFR inhibitor group. ^##P<0.01 compared with the control group; **P<0.01 compared with the upregulated miRNA-223 expression group.

Figure 7. — Inhibition of EGFR increases the anticancer effects of miRNA-223 in A549 cells. (A) Cell proliferation, (B and C) migration rate. Control, control group; miR-223, upregulated miRNA-223 expression group; EGFR inhibitor, upregulated miRNA-223 expression and EGFR inhibitor group. ^##P<0.01 compared with the control group; **P<0.01 compared with the upregulated miRNA-223 expression group. Inhibition of EGFR increases the anticancer effects of miRNA-223 in A549 cells. (D and E) Apoptosis rate, (F) LDH activity, and (G) caspase-3/9 activity. Control, control group; miR-223, upregulated miRNA-223 expression group; EGFR inhibitor, upregulated miRNA-223 expression and EGFR inhibitor group. ^##P<0.01 compared with the control group; **P<0.01 compared with the upregulated miRNA-223 expression group.