Figure 2. Gene regulatory network (The Cancer Genome Atlas colorectal cancer from cBioportal) with SRC proto-oncogene, non-receptor tyrosine kinase(SRC) in the center (SRC is highly similar to the v-src gene of Rous sarcoma virus.), polio virus receptor (PVR) nearby, neighbors filtered by percentagealteration: A: No alteration, B: 10.3% alteration, C: 32.5% alteration. SRC, adenopolyposis coli (APC) and Kirsten rat sarcoma virus (KRAS) are allinvolved in colorectal cancer. Note that in C, APC and KRAS are strongly expressed (red), SRC less so (pink), and PVR not at all (white).
