Table 2.
General baseline characteristics (n=57)
| Characteristic | Topical tranexamic acid group (n=29) | Control group (n=28) | p-value |
|---|---|---|---|
| Age (yr) | 52 (33.5–55.5) | 51.5 (33.5–58.0) | 0.45a) |
| Sex | 0.23b) | ||
| Male | 20 (69.1) | 15 (53.6) | |
| Female | 9 (30.9) | 13 (46.4) | |
| Body mass index (kg/m2) | 22.2±3.3 | 22.3±3.2 | 0.87c) |
| Thoracolumbar Injury Classification and Severity score | 0.12b) | ||
| 5 | 21 (72.4) | 26 (92.9) | |
| 6 | 1 (3.5) | - | |
| 7 | 7 (24.1) | 2 (7.1) | |
| Mechanism of injury | 0.98b) | ||
| Fall from height | 20 (69.0) | 18 (64.3) | |
| Motorcycle accident | 4 (13.8) | 4 (14.2) | |
| Motor vehicle accident | 4 (13.8) | 5 (17.9) | |
| Stuck by a heavy object | 1 (3.4) | 1 (3.6) | |
| Fractured level | 0.29b) | ||
| T11 | 3 (10.3) | 1 (3.6) | |
| T12 | 8 (27.6) | 5 (17.9) | |
| L1 | 16 (55.2) | 16 (57.1) | |
| L2 | 2 (6.9) | 6 (21.4) | |
| American Society of Anesthesiologists physical status | 0.56b) | ||
| 1 or 2 | 22 (75.9) | 23 (82.1) | |
| 3 | 7 (24.1) | 5 (17.9) | |
| Preoperative anterior body height loss (%) | 49.4±14.3 | 46.0±13.0 | 0.36c) |
| Fracture body angle (°) | 19.9±6.1 | 20.2±8.3 | 0.89c) |
| Operative time (min) | 98.6±18.2 | 91.0±18.6 | 0.12c) |
| Intraoperative fluid volume (mL) | 1,753.5±365.5 | 1,882.1±434.5 | 0.23c) |
| Intraoperative total estimated blood loss (mL) | 260.3±166.0 | 265.0±146.6 | 0.90c) |
Values are presented as median (interquartile range), number (%), or mean±standard deviation.
a)
Result of Mann–Whitney U-test.
b)
Result of chi-square test.
c)
Result of two sample t -test.