Table 3C.

Molecular function of differentially expressed proteins (DEPs).

DEPs	Item description	Protein count and matching proteins
Downregulated DEPs	Protein binding	39: ADAM11, ANGPTL2, APLN, CCK, CCL15, CCL7, CCR1, CCR2, CDH5, CER1, CSK, CTNNB1, EDA, ERBB3, ERBB4, ESRRA, FASLG, FGF8, HGF, HTRA2, ICAM2, IFNB1, IL17B, IL17C, IL17F, IL24, IL26, LIF, NBL1, NGF, NPY, NRG2, NRTN, NTF3, PGF, SPARC, TF, TIMP2, VWF
	Receptor binding	31: ADAM11, ANGPTL2, APLN, CCK, CCL15, CCL7, CCR2, CDH5, CSK, CTNNB1, EDA, ERBB4, FASLG, FGF8, HGF, ICAM2, IFNB1, IL17B, IL17C, IL17F, IL24, IL26, LIF, NGF, NPY, NRG2, NRTN, NTF3, PGF, TF, VWF
	Cytokine activity	9: CCL15, CCL7, IFNB1, IL17B, IL17C, IL17F, IL24, IL26, LIF
	Cytokine receptor binding	7: CCL15, CCL7, CCR2, IFNB1, LIF, NGF, NTF3
	Growth factor activity	6: FGF8, HGF, LIF, NGF, NTF3, PGF
	Chemoattractant activity	4: CCL15, FGF8, HGF, NTF3
	Cytokine binding	4: CCR1, CER1, IL17F, NBL1
	C-C chemokine receptor activity	3: CCBP2, CCR1, CCR2
	Morphogen activity	2: CER1, NBL1
	BMP binding	2: CER1, NBL1
Upregulated DEPs	Protein binding	27: ADAM17, APOE, CCL1, CCR7, CDH13, CNTF, CRP, CTSB, DLL1, FGF18, FST, GAL, GAST, GCG, HSPB6, IGF2, IL34, ITGA2B, KITLG, MMP9, NTF4, RARRES2, SAA1, SCARB2, SMAD4, SMAD5, TFRC
	Receptor binding	16: ADAM17, APOE, CCL1, CNTF, CRP, DLL1, FGF18, GAL, GAST, GCG, IGF2, IL34, KITLG, NTF4, RARRES2, SAA1
	Endopeptidase activity	7: ADAM17, CTSB, KLK14, LGMN, MMP9, PAPPA, PGA5
	Growth factor activity	4: CNTF, FGF18, IGF2, NTF4
	Lipoprotein particle binding	3: APOE, CDH13, CRP
	Interleukin-6 receptor binding	2: ADAM17, CNTF