Table I.
Association between FLOT2 expression and other clinicopathological features in colorectal carcinoma.
| FLOT2 expression | |||
|---|---|---|---|
| Characteristic | Low/no (n=61) | High (n=119) | P-value |
| Sex | 0.979 | ||
| Male | 32 | 61 | |
| Female | 29 | 58 | |
| Age, years | 0.829 | ||
| <60 | 17 | 35 | |
| ≥60 | 44 | 84 | |
| Tumor size, cm | 0.730 | ||
| <5 | 25 | 50 | |
| ≥5 | 36 | 69 | |
| Tumor location | 0.497 | ||
| Colon | 20 | 30 | |
| Rectum | 41 | 89 | |
| Histological type | 0.189 | ||
| NMC | 58 | 94 | |
| MC | 3 | 25 | |
| Differentiation | 0.517 | ||
| Well | 16 | 25 | |
| Moderate | 22 | 35 | |
| Poor | 23 | 59 | |
| Depth of invasion | 0.024 | ||
| T1 | 18 | 19 | |
| T2 | 19 | 26 | |
| T3 | 14 | 34 | |
| T4 | 10 | 40 | |
| Lymph node metastasis | 0.005 | ||
| N0 | 33 | 41 | |
| N1-2 | 28 | 78 | |
| Distant metastasis | 0.008 | ||
| M0 | 55 | 101 | |
| M1 | 6 | 18 | |
| AJCC stage | 0.011 | ||
| I+II | 30 | 46 | |
| III+IV | 31 | 73 | |
Distant metastasis includes peritoneum, liver and bone metastasis. FLOT2, flotillin 2; AJCC, American Joint Committee on Cancer; MC, mucinous adenocarcinoma; NMC, non-mucinous adenocarcinoma.