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Digoxin could not enhance the cytotoxicity of gemcitabine and inhibit the Nrf2 signaling in SW1990 and Panc-1 cells. (A–B) Effects of digoxin on chemosensitivity of SW1990 and Panc-1 cells to gemcitabine. (C–D) Effects of digoxin on the protein levels of Nrf2 in SW1990 and Panc-1 cells. Data were expressed as mean ± SD, and the results were representative of three independent experiments.
