Table 2.
Determination of IC50 of different anticancer drugs.
| Group | SW1990 | SW1990/Gem | RI | Panc-1 | Panc-1/Gem | RI |
|---|---|---|---|---|---|---|
| Gemcitabine (μM) | 9.33 ± 0.9 | 532.15 ± 26.13 | 57.04 | 7.85 ± 0.56 | 296.34 ± 22.17 | 37.75 |
| Etoposide (μM) | 117.46 ± 14.02 | 624.52 ± 44.89 | 5.32 | 102.7 ± 9.35 | 439.24 ± 37.58 | 4.28 |
| Paclitaxel (nM) | 35.43 ± 4.34 | 298.15 ± 37.68 | 8.41 | 32.67 ± 2.97 | 214.82 ± 16.45 | 6.58 |
| Cisplatin (μM) | 58.74 ± 4.82 | 187.23 ± 21.09 | 3.19 | 65.38 ± 7.74 | 158.39 ± 13.29 | 2.42 |
| 5-FU (μM) | 33.05 ± 2.85 | 183.68 ± 8.4 | 5.56 | 39.14 ± 1.99 | 175.74 ± 11.55 | 4.49 |
| Ara-C (μM) | 1.38 ± 0.23 | 16.11 ± 1.43 | 11.67 | 1.21 ± 0.09 | 11.68 ± 0.7 | 9.65 |
| Doxorubicin (μM) | 4.35 ± 0.59 | 27.85 ± 1.89 | 6.4 | 4.66 ± 0.29 | 23.59 ± 1.64 | 5.06 |
IC50 values of different anticancer drugs were detected by using MTT assay. Data were expressed as mean ± SD of three independent experiments.