Table II.
Differentially expressed piRNAs and their corresponding fold changes in expression.
| piRNA | Fold change | P-value | Sequence (5′-3′) |
|---|---|---|---|
| Non-smokersa | |||
| piR-258904 | 3.26275255 | 0.031 | TGAGAACATTGGATTTTTCACCCTAG |
| piR-35373 | 2.76213293 | 0.031 | TCCACACACCAAGCCTTGGATTGGTCTGG |
| piR-266308 | 2.57372618 | 0.019 | ACGGCCCTGGCGGAGCGC |
| piR-34946 | 2.29238305 | 0.027 | TCATGAGGTCAGGAGTTCAAGACCAGCC |
| All patientsb | |||
| piR-58510 | 5.242446202 | 0.0048 | GCCTGGCCAACATGGCAAAACGTCGTGTCTA |
| piR-34946 | 3.446885753 | 0.0014 | TCATGAGGTCAGGAGTTCAAGACCAGCC |
| piR-43219 | 3.389853452 | 0.0032 | CACCTTGGGAGGCCAAGGCAGGCAGATCAT |
| piR-38034 | 3.316586523 | 0.0068 | TCGCTTGAACCTGGAAGGCGGAGGTTGC |
| piR-70732 | 0.359078784 | 0.057 | TGATGATGGTGGTGGTGGTGTCGGTGA |
a
piRNA expression was compared between alcohol drinkers and non-drinkers in the non-smoking cohort (n=18).
b
piRNA expression was compared between alcohol drinkers and non-drinkers in all patients (n=40). piRNA, PIWI-interacting RNA; PIWI, P-element-induced wimpy testis.