Figure 4.

Investigation on proteins potentially interacting with HMGB3. (A) Proteins that may interact with HMGB3 were obtained using STRING online database with the confidence score set at 0.4; each node represent a protein, and each edge between two nodes represents the protein-protein interaction. The width of each edge represents the confidence score of that protein-protein interaction. (B) GO annotation of predicted HMGB3 interacting proteins; number of genes enriched to each GO term was plotted to the upper x-axis in box-plot fashion, and the -log₂ (p) of each annotated term was plotted to the lower x-axis in dotted-linear graph fashion. HMGB3, high mobility group box 3; GO, Gene Ontology.