Figure 1.

Pristimerin inhibits proliferation of CAL-27 and SCC-25 cells. (A) Molecular structure of pristimerin compound. (B) Cells were treated with increasing concentrations of pristimerin for 72 h, and cell viability was determined by MTS assay. (C) Cell viability was measured after cells were treated with cisplatin and 5-fluorouracil. (D) Colony formation ability of CAL-27 and SCC-25 cells was determined following treatment with the indicated concentrations of pristimerin for 24 h or with 1 µM for various durations. **P<0.01 and ***P<0.001 vs. control.