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. 2019 Feb 4;7:2050312119828261. doi: 10.1177/2050312119828261

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© The Author(s) 2019

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 9. — (a) The forest plot of odds ratios (ORs) of recurrent stroke (none/trace right to left shunt) with device closure versus medical therapy. Sizes of data markers are proportional to the weight of each study in the meta-analysis. Horizontal bars represent the 95% confidence interval of individual trials. OR measured by random effects for recurrent stroke (none-trace right to left shunt) was recorded with 95% confidence interval (95% CI) and p value. OR = 0.60, 95% CI = 0.19–1.84, p = 0.37, I² = 51.8%. (b) The forest plot of ORs of recurrent stroke (moderate/large right to left shunt) with device closure versus medical therapy. Sizes of data markers are proportional to the weight of each study in the meta-analysis. Horizontal bars represent the 95% confidence interval of individual trials. OR measured by random effects for recurrent stroke (moderate/large right to left shunt) was recorded with 95% confidence interval (95% CI) and p value. OR = 0.29, 95% CI = 0.13–0.69, p = 0.37, I² = 37.1%.