Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Sep 25;19(3):391–406. doi: 10.1093/biostatistics/kxx048

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/about_us/legal/notices)

PMC Copyright notice

Fig. 1. — (a) Illustration of the typical data format with two tissues. Genotype data is available for SNPs and each of samples. Expression measurements are available for genes; sample sets for different tissues may not be the same. (b) z-statistics for lung and thyroid: density plot for all local gene–SNP pairs (top), and scatter plot for significant local gene–SNP pairs with tissue specificity by gray scale (bottom). The gene–SNP pairs deemed insignificant are omitted, leading to the white space at the center of the plot. The remaining points are colored according to their assessed tissue specificity: dark gray points correspond to the Lung-specific eQTL; black points correspond to the Thyroid-specific eQTL; light gray points correspond to the cross-tissue eQTL.

Inline graphic — (a) Illustration of the typical data format with two tissues. Genotype data is available for SNPs and each of samples. Expression measurements are available for genes; sample sets for different tissues may not be the same. (b) z-statistics for lung and thyroid: density plot for all local gene–SNP pairs (top), and scatter plot for significant local gene–SNP pairs with tissue specificity by gray scale (bottom). The gene–SNP pairs deemed insignificant are omitted, leading to the white space at the center of the plot. The remaining points are colored according to their assessed tissue specificity: dark gray points correspond to the Lung-specific eQTL; black points correspond to the Thyroid-specific eQTL; light gray points correspond to the cross-tissue eQTL.