Figure 5.

YY1 silencing inhibits anaplastic thyroid cancer cell growth. (A and B) The western blot analysis assay demonstrated the protein expression of YY1 in SW1736 and 8305C cells. (C and D) The cell viability was detected with a Cell Counting Kit-8 assay. (E and F) The proliferation was detected with a colony formation assay. (G and H) YY1 silencing suppressed tumor growth in nude mice. (G) Representative images of tumors from the implanted mice. (H) The tumor weight was measured. *P<0.05. YY1, Yin Yang-1; si-YY1, small interfering YY1; shYY1, short hairpin YY1.