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. 2019 Feb 6;13:12. doi: 10.1186/s13036-018-0132-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Schematic representation of the cardiovascular modeling process for patient specific diseases diagnostics. Processes 1, 2 and 3 show the sequential steps whereas step 4 and 5 shows conditions for real time processing. a. Thick and calcific Mitral valve with decreased opening in case of Chronic Rheumatic Heart Disease, (b). Parasternal Short Axis view of Mitral valve showing thickened anterior and posterior leaflets with reduced valve area, (c). Four Chamber view showing thickened Tricuspid Valve (yellow arrow) suggestive of organic Tricuspid valve disease and thick and calcific Mitral valve (red arrow) in case of Rheumatic Heart Disease, (d). 3D mesh for the volume generated geometry. e. Numerical setup for the problem in CFD software, F. Result post processing.)