Table 3.
Trait | Dependent variable | Polygenic effect | FDRa | Bonferronib | λ |
---|---|---|---|---|---|
BW0 | Phen | 1213 | 64 | 1.92 | |
7 | 3 | 0.96 | |||
LOCO | 2268 | 125 | 2.22 | ||
LOCO_pruned | 394 | 43 | 1.97 | ||
LOCO_SEG40 | 1811 | 103 | 2.06 | ||
LOCO_SEG441 | 80 | 17 | 1.29 | ||
LOCO_SEG864 | 41 | 12 | 1.18 | ||
LOCO + PC20 | 1132 | 73 | 1.90 | ||
LOCO + CHR_PC20 | 16 | 7 | 0.93 | ||
dDRP | 1463 | 104 | 1.96 | ||
15 | 6 | 0.96 | |||
LOCO | 2212 | 163 | 2.19 | ||
LOCO_pruned | 414 | 54 | 1.91 | ||
LOCO_SEG40 | 1802 | 143 | 2.07 | ||
LOCO_SEG441 | 103 | 23 | 1.28 | ||
LOCO_SEG864 | 57 | 15 | 1.17 | ||
LOCO + PC20 | 1180 | 108 | 1.87 | ||
LOCO + CHR_PC20 | 13 | 8 | 0.90 | ||
BW23 | Phen | 11 | 0 | 1.17 | |
0 | 0 | 0.99 | |||
LOCO + CHR_PC20 | 0 | 0 | 0.66 | ||
LOCO + CHR_PC10 | 0 | 0 | 0.93 | ||
dDRP | 22 | 5 | 1.33 | ||
3 | 2 | 1.00 | |||
LOCO + CHR_PC20 | 0 | 0 | 0.70 | ||
LOCO + CHR_PC10 | 1 | 1 | 0.96 | ||
BW1314 | Phen | 47 | 14 | 1.46 | |
5 | 3 | 0.97 | |||
LOCO + CHR_PC20 | 2 | 2 | 0.72 | ||
LOCO + CHR_PC10 | 7 | 4 | 0.98 | ||
dDRP | 50 | 17 | 1.45 | ||
7 | 6 | 0.97 | |||
LOCO + CHR_PC20 | 3 | 3 | 0.72 | ||
LOCO + CHR_PC10 | 12 | 6 | 0.97 |
FDR: false discovery rate; Bonferroni: Bonferroni correction; λ: inflation factor; BW0: body weight recorded at birth; BW23: body weight recorded at 2 to 3 month of age; BW1314: body weight recorded at 13 to 14 months of age; dDRP: de-regressed proofs for the direct genetic effect; mDRP: de-regressed proofs for the maternal genetic effect; LOCO_pruned: LOCO based on pruned SNPs
aNumber of significant SNPs according to false discovery rate
bNumber of significant SNPs according to Bonferroni-correction