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. 2019 Feb 6;20:28. doi: 10.1186/s12931-019-0979-0

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Comparisons poractant-α vs bovine surfactants for airleaks (a-b) and lung haemorrhage (c-d). Panels a (1154 patients) and c (1034 patients) illustrate meta-analyses of 200 mg/kg poractant-α vs bovine surfactants; panels b (1442 patients) and d (1242 patients) illustrate meta-analyses of any dose of poractant-α vs bovine surfactants. Poractant-α and bovine surfactants are considered as treatment (Trt) and control (Ctrl) arm, respectively; events per arm and odds ratio (95%CI) are reported. All analyses have been performed with random effect model