Table 1.
Ext1 | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
EmiR-21 | EmiR-222 | EmiR-221 | EmiR-105 | EmiR-155 | ||||||||
n | Median | p value | Median | p value | Median | p value | Median | p value | Median | p value | ||
Age (years) | < 50 | 27 | 1.518 | 0.983 | 1.506 | 0.966 | 1.161 | 0.667 | 11.199 | 0.897 | 1.901 | 0.302 |
≥ 50 | 20 | 1.671 | 1.592 | 1.375 | 8.362 | 3.247 | ||||||
Menopause | Pre | 30 | 1.579 | 0.330 | 1.585 | 0.658 | 1.399 | 0.232 | 9.474 | 0.947 | 1.904 | 0.250 |
Post | 17 | 1.424 | 1.424 | 1.088 | 8.597 | 3.370 | ||||||
T | T1–T2 | 27 | 1.265 | 0.039* | 1.506 | 0.813 | 1.173 | 0.780 | 3.851 | 0.067 | 1.906 | 0.093 |
T3–T4 | 20 | 1.787 | 1.556 | 1.379 | 22.184 | 4.073 | ||||||
N | 0 | 20 | 1.443 | 1.000 | 1.315 | 0.342 | 1.197 | 0.733 | 8.362 | 0.846 | 2.436 | 0.770 |
1–3 | 23 | 1.543 | 1.584 | 1.088 | 30.239 | 3.019 | ||||||
Estrogen receptor | Negative | 13 | 1.615 | 0.812 | 2.992 | 0.161 | 1.221 | 0.812 | 49.757 | 0.140 | 2.776 | 0.981 |
Positive | 34 | 1.462 | 1.417 | 1.155 | 7.072 | 2.892 | ||||||
Progesterone receptor | Negative | 17 | 1.615 | 0.773 | 2.992 | 0.018* | 1.597 | 0.465 | 49.757 | 0.116 | 2.776 | 0.947 |
Positive | 30 | 1.403 | 1.271 | 1.064 | 7.072 | 2.778 | ||||||
HER2 | Negative | 36 | 1.531 | 0.466 | 1.465 | 0.880 | 1.149 | 0.563 | 8.362 | 0.744 | 3.117 | 0.421 |
Positive | 11 | 1.265 | 2.019 | 1.596 | 14.130 | 1.055 | ||||||
KI67 | < 20% | 8 | 1.157 | 0.458 | 0.850 | 0.050 | 1.279 | 0.573 | 3.380 | 0.103 | 2.219 | 0.373 |
≥ 20 | 37 | 1.518 | 1.584 | 1.161 | 14.130 | 3.019 | ||||||
Perou’s classification | Basal-like | 8 | 1.566 | 0.976 | 3.179 | 0.037* | 1.191 | 0.986 | 39.998 | 0.306 | 4.127 | 0.495 |
Luminal A | 7 | 1.543 | 0.803 | 1.656 | 3.389 | 1.901 | ||||||
Luminal B | 27 | 1.424 | 1.513 | 1.139 | 7.750 | 3.215 | ||||||
HER2neu | 5 | 1.960 | 2.094 | 1.597 | 60.097 | 1.055 |
Wilcoxon signed-rank test and Kruskal-Wallis test were used. Abbreviations: CTCs circulating tumor cells, Ext1 basal extraction, Ext2 extraction during neoadjuvant treatment, T tumor size, N lymph node status. *p > 0.05