Table 2.

The effect of different concentrations of dialysate bicarbonate on intradialytic change of plasma calcium, PTH, bicarbonate, albumin, TP, blood pH and CMB

n = 10 (HDF)	26_DHCO3	32_DHCO3	Pa
Plasma PTH pre (pmol/L)	291 ± 111	284.5 ± 125	0.9
Plasma PTH post (pmol/L)	180 ± 79***	304 ± 126	0.02
CMB (mg)	−309 ± 329	−108 ± 215	0.12
Plasma tCa pre (mmol/L)	2.18 ± 0.06	2.23 ± 0.10	0.17
Plasma tCa post (mmol/L)	2.27 ± 0.09*	2.24 ± 0.13	0.55
Plasma iCa pre (mmol/L)	1.178 ± 0.062	1.189 ± 0.054	0.66
Plasma iCa post (mmol/L)	1.253 ± 0.05***	1.150 ± 0.026*	<0.001
Plasma tCa(corr) pre (mmol/L)	2.19 ± 0.09	2.23 ± 0.11	0.31
Plasma tCa(corr) post (mmol/L)	2.22 ± 0.09	2.19 ± 0.09	0.60
Plasma TP pre (g/dL)	6.71 ± 0.60	6.68 ± 0.53	0.91
Plasma TP post (g/dL)	7.28 ± 0.76***	7.10 ± 0.71**	0.59
Plasma albumin pre (g/dL)	4.08 ± 0.21	4.11 ± 0.14	0.71
Plasma albumin post (g/dL)	4.38 ± 0.27**	4.34 ± 0.32**	0.77
Blood pH pre	7.364 ± 0.040	7.355 ± 0.035	0.61
Blood pH post	7.380 ± 0.021	7.450 ± 0.025***	<0.001
Blood HCO3 pre (mmol/L)	21.2 ± 1.6	20.9 ± 1.4	0.62
Blood HCO3 post (mmol/L)	21.6 ± 0.74	26.7 ± 0.9***	<0.001
ΔPTH (pmol/L)	−110.5 ± 66.8	19.7 ± 103.4	<0.01
ΔtCa (mmol/L)	0.08 ± 0.09	0.01 ± 0.13	0.12
ΔiCa (mmol/L)	0.075 ± 0.043	−0.039 ± 0.042	<0.001
ΔtCa(corr) (mmol/L)	0.03 ± 0.08	−0.04 ± 0.11	0.11
ΔTP (g/dl)	0.57 ± 0.36	0.42 ± 0.38	0.38
Δalbumin (g/dl)	0.30 ± 0.22	0.23 ± 0.22	0.48
Δ${\text{HCO}}_3^{-}$ (mmol/L)	0.32 ± 1.72	5.81 ± 1.57	<0.001
ΔpH	0.017 ± 0.03	0.095 ± 0.022	<0.001
Ultrafiltration volume (mL)	2360 ± 997	2330 ± 884	0.9

Data are shown as means ± SD.

post, postdialysis; pre, predialysis; Δ, intradialytic change.

^aP-value of unpaired test between groups using dialysate bicarbonate 26 and 32 mmol/L.

*P < 0.05 compared with pre-dialysis plasma concentration (paired test).

**P < 0.01 compared with pre-dialysis plasma concentration (paired test).

***P < 0.001 compared with pre-dialysis plasma concentration (paired test).