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(A) Lymph node biopsy and (B) peripheral smear in adult T-cell lymphoma/leukemia (ATL). The neoplastic cells in ATL characteristically have a flower-like or clover-shaped appearance. By flow cytometry, they express CD2, CD4, CD5, CD45RO, CD29, and T-cell receptor αβ and do not express CD7, CD8, or CD26. CD3 expression is often reduced. Photographs courtesy of Ahmet Dogan.
