Table 2.
The histogram parameters of MS lesions
| CE | NE | Z value | P-value | |
|---|---|---|---|---|
|
| ||||
| Ktrans | ||||
| Skewness | 0.6496 (0.0261 – 1.0477) | 0.0389 (−0.2269 to 0.4843) | −2.149 | 0.032 |
| Kurtosis | −0.4065 (−0.8203 to 0.8362) | −0.7569 (−1.1224 to −0.1806) | −1.982 | 0.048 |
| Vp | ||||
| Skewness | −0.0338 (−0.2137 to 0.6700) | 0.2865 (0.0198 – 0.6297) | −1.122 | 0.262 |
| Kurtosis | −0.8759 (−1.0820 to 0.1161) | −0.7647 (−1.0969 to −0.1817) | −0.024 | 0.981 |
| CBF | ||||
| Skewness | 0.1264 (−0.1465 to 0.5258) | 0.2588 (−0.1471 to 0.5421) | −0.215 | 0.830 |
| Kurtosis | −0.9235 (−1.2924 to −0.5948) | −0.7392 (−1.0720 to −0.0897) | −1.408 | 0.159 |
| CBV | ||||
| Skewness | 0.2741 (−0.0058 to 0.5472) | 0.2262 (0.0333 – 0.4631) | −0.382 | 0.702 |
| Kurtosis | −0.8579 (−1.2466 to −0.4580) | −0.7682 (−1.1318 to −0.1271) | −0.812 | 0.417 |
Notes: Median (P25–P75) was used to describe the histogram characteristic of MS lesions. The Mann–Whitney U test in SPSS 21 software was used to compare the differences of these parameters.
Abbreviations: CBF, cerebral blood flow; CE, contrast-enhancing; CBV, cerebral blood volume; Ktrans, volume transfer constant; MS, multiple sclerosis; NE, non-enhancing; Vp, fractional plasma volume.