Table 4.
Agreement between self-reported and tumour registry for cancer (all-sites), among Alaska EARTH participants, stratified by demographic and clinical characteristics.a
| Sensitivity |
Specificity |
PPV |
NPV |
Kappa |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| (%) | 95% CIa | (%) | 95% CI | (%) | 95% CI | (%) | 95% CI | (%) | 95% CI | |
| Cancer (all-sites) | ||||||||||
| Sex | ||||||||||
| Male | 95.6 | 78.1–99.9 | 99.3 | 98.6–99.6 | 66.7 | 48.2–82.0 | 99.9 | 99.6–100.0 | 0.78 | 0.66–0.90 |
| Female | 84.2 | 74.0–91.6 | 98.1 | 97.4–98.6 | 59.8 | 49.9–69.2 | 99.5 | 99.0–99.7 | 0.68 | 0.61–0.77 |
| Age at enrolment (years) | ||||||||||
| 18–50 | 90 | 74.3–98.0 | 98.8 | 98.3–99.2 | 45.9 | 33.1–59.2 | 99.9 | 99.7–99.9 | 0.6 | 0.48–0.72 |
| 50+ | 85.3 | 74.6–92.7 | 97.7 | 96.5–98.6 | 73.4 | 62.3–82.7 | 98.9 | 98.0–99.5 | 0.77 | 0.69–0.85 |
| Education (years) | ||||||||||
| <12 | 86.1 | 70.5–95.3 | 98.9 | 98.0–99.7 | 79.5 | 63.5–90.7 | 99.4 | 98.5–99.8 | 0.81 | 0.72–0.91 |
| ≥12 | 89.4 | 76.9–96.5 | 98.1 | 97.3–98.7 | 54.6 | 42.8–65.9 | 99.7 | 99.1–99.8 | 0.67 | 0.57–0.76 |
| Residence | ||||||||||
| Rural | 76.3 | 59.8–88.6 | 98.9 | 98.4–99.4 | 59.2 | 44.2–73.0 | 99.5 | 99.1–99.8 | 0.66 | 0.54–0.78 |
| Urban | 93.4 | 84.1–98.2 | 98.1 | 97.3–98.7 | 62.6 | 51.9–72.6 | 99.8 | 99.4–99.9 | 0.74 | 0.66–0.82 |
| Primary language | ||||||||||
| English | 94.8 | 85.9–98.9 | 98.3 | 97.8–98.8 | 58.3 | 47.8–68.3 | 99.9 | 99.6–99.9 | 0.71 | 0.63–0.80 |
| Non-English/both | 73.7 | 56.9–86.6 | 98.8 | 98.0–99.4 | 66.7 | 52.4–80.4 | 99.2 | 98.5–99.6 | 0.69 | 0.57–0.81 |
| EARTH study region | ||||||||||
| Southcentral | 93.8 | 82.8–98.7 | 97.8 | 97.0–98.6 | 61.6 | 49.5–72.8 | 99.8 | 99.3–99.9 | 0.73 | 0.64–0.82 |
| Southeast | 83.9 | 66.3–94.6 | 98.4 | 97.3–99.1 | 65 | 48.3–79.4 | 99.4 | 98.6–99.8 | 0.72 | 0.60–0.84 |
| Southwest | 75 | 50.9–91.3 | 99.2 | 98.6–99.6 | 55.6 | 35.3–74.5 | 99.7 | 99.2–99.9 | 0.63 | 0.47–0.79 |
aFor the purposes of these comparisons, ANTR was treated as the reference. However, PPV and NPV, respectively, reflect sensitivity and specificity if self-report is substituted for the reference.