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Potency of GYY4137 on relaxation of phenylephrine-preconstricted uterine (UA) and mesenteric (MA) arteries in nonpregnant (NP) and pregnant (P) rats.
| Artery | n | pD2 value | P value |
|---|---|---|---|
| NP-UA | 12–18 | 5.97 ± 0.01 | <0.001 |
| P-UA | 12–18 | 7.43 ± 0.02*** | <0.001 |
| P-MA | 12–18 | ND | ND |
***P < 0.001 vs. NP-UA; P < 0.001 (ANOVA) vs. control for the same vessel; ND: non-detectable.
