Table 2.
Imaging characteristics by presence of mitral annular calcification (prevalence) and mitral annular 18F-fluoride uptake (disease activity).
| Imaging Characteristics | MAC- (n=69) |
MAC+ (n=35) |
p | 18F-fluoride- (n=66) |
18F-fluoride+ (n=36) |
p |
|---|---|---|---|---|---|---|
| Aortic valve by echocardiography | ||||||
| Control, n (%) | 3 (4.4) | 2 (5.7) | 0.034 | 4 (6.1) | 1 (2.8) | 0.012 |
| Sclerosis, n (%) | 16 (23.3) | 2 (5.7) | 17 (25.8) | 1 (2.8) | ||
| Mild stenosis, n (%) | 20 (29.0) | 5 (14.3) | 17 (25.8) | 7 (19.4) | ||
| Moderate stenosis, n (%) | 18 (26.1) | 15 (42.9) | 18 (27.3) | 15 (41.7) | ||
| Severe stenosis, n (%) | 12 (17.4) | 11 (31.4) | 10 (15.2) | 12 (33.3) | ||
| AVC calcium score, AU | 801 (298-2174) | 1501 (600-3314) | 0.030 | 771 (309-2076) | 1598 (1007-3230) | 0.003 |
| MAC calcium score, AU | 0 | 837 (300-2129) | - | 0 | 834 (139-2107) | - |
| Aorta calcium score, AU | 894 (190-2548) | 1733 (396-7984) | 0.058 | 997 (144-3181) | 1378 (374-4036) | 0.170 |
| Aortic valve 18F-fluoride TBRmax | 2.44 (1.91-2.99) | 2.58 (2.21-3.14) | 0.192 | 2.34 (1.96-2.91) | 2.74 (2.38-3.18) | 0.028 |
| Mitral annulus 18F-fluoride TBRmax | 1.30 (1.22-1.49) | 2.32 (1.81-3.27) | <0.001 | 1.29 (1.22-1.41) | 2.30 (1.84-3.07) | <0.001 |
| Coronary artery18F-fluoride TBRmax | 1.50 (1.33-1.75) | 1.60 (1.35-2.09) | 0.274 | 1.50 (1.35-1.76) | 1.59 (1.35-2.02) | 0.590 |
| 18F-fluoride TBRmax in aorta | 2.06 (1.82-2.28) | 2.14 (1.19-2.38) | 0.081 | 2.05 (1.84-2.26) | 2.20 (1.91-2.50) | 0.060 |
| Aortic valve 18F-FDG TBRmax * | 1.52 (1.44-1.63) | 1.39 (1.33-1.63) | 0.072 | 1.51 (1.40-1.63) | 1.46 (1.35-1.68) | 0.83 |
| Mitral annulus 18F-FDG TBRmax * | 1.17 (1.12-1.24) | 1.44 (1.37-1.58) | <0.001 | 1.17 (1.12-1.26) | 1.38 (1.24-1.56) | 0.002 |
| Aorta 18F-FDG TBRmax | 1.84 (1.69-1.94) | 1.68 (1.50-1.78) | 0.002 | 1.83 (1.68-1.92) | 1.69 (1.61-1.83) | 0.116 |
Continuous variables are presented as median (IQR).
*
n=33 patient with failed myocardial FDG suppression were excluded