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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Curr Opin Nephrol Hypertens. 2019 Mar;28(2):120–127. doi: 10.1097/MNH.0000000000000477

Figure 2. Structure of the AGTR1 with documented sites of interaction with Gα subunits highlighted.

Figure 2.

Structural mapping studies performed by Shibata et al (47) and Shirai et al (48) identified critical regions within the human AGTR1 and rodent Agtr1a essential for association and activation of Gαq, Gαi and Gαo.