TABLE 3.
Genes and Single Nucleotide Polymorphisms Associated With Risk for Hippocampal Sclerosis of Aging
Gene | SNP | Experiment that Linked the Gene to HS-Aging: SNP-Focused or GWAS | Replicated? | References |
---|---|---|---|---|
GRN | rs5848 | SNP-focused | Yes | ( 124 , 144 , 173 , 174 ) |
TMEM106B | rs1990622 | SNP-focused | Yes | ( 170 , 174 , 194 , 196 , 208 , 209 ) |
ABCC9 | rs704180 | GWAS | Yes | ( 24 , 151 , 174 , 58 ) a |
KCNMB2 | rs9637454 | GWAS | No | ( 210 ) |
a Reference ( 58 ) refers only to ABCC9 association with brain arteriolosclerosis.