Table 2. Distribution of genotype and allele among RA patients and controls.

Study author	RA cases					Healthy control					P-HWE	MAF
	GG	GA	AA	G	A	GG	GA	AA	G	A
TIM-1 rs41297579 G>A (-1454)
Chae et al.	216	71	6	503	83	220	75	7	515	89	0.839	0.147
Xu et al.	86	26	4	201	35	90	26	2	205	31	0.938	0.127
Mosaad et al.	110	14	4	234	22	98	24	3	220	30	0.309	0.12
Study author	RA cases					Healthy control					P-HWE	MAF
	TT	TG	GG	T	G	TT	TG	GG	T	G
TIM-3 rs1036199 G>T(+4259)
Chae et al.	203	93	0	499	93	256	63	0	575	63	0/05	0/098
Song et al.	355	31	0	741	31	365	24	0	754	24	0/53	0/03
Xu et al.	198	28	0	424	21	244	7	0	455	7	0/822	0/013
Xu et al.	90	13	0	193	13	103	5	0	211	5	0/805	0/023
Study author	RA cases					Healthy control					P-HWE	MAF
	GG	GT	TT	G	T	GG	GT	TT	G	T
TIM-3 rs10515746T>G (-574)
Song et al.	343	23	0	709	23	378	11	0	767	11	0/777	0/014
Xu et al.	203	23	0	429	23	212	19	0	443	19	0/514	0/041
Xu et al.	100	3	0	203	3	85	21	2	191	25	0/602	0/115
Study author	RA cases					Healthy control					P-HWE	MAF
	GG	GA	AA	G	A	GG	GA	AA	G	A
TIM-4 rs7700944 G>A
Xu et al.	134	65	11	332	88	76	113	8	267	129	0	0/327
Xu et al.	77	135	2	289	139	135	70	6	341	85	0/387	0/194
Zakeri et al.	68	47	5	183	57	77	41	2	195	45	0/138	0/187
Mosaad et al.	29	87	12	145	111	99	23	3	221	29	0/25	0/116

P-HWE, p-value for Hardy–Weinberg equilibrium; MAF, minor allele frequency of control group