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. 2019 Feb 7;14(2):e0211716. doi: 10.1371/journal.pone.0211716

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© 2019 Ammer-Herrmenau et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 2 — Mice were injected with PBS i.p. (Sham) or subjected to sepsis induction (PCI) or sepsis-induction plus IL-7 treatment (PCI + IL-7). At the indicated time points between d8 and d113 after PCI at least 6 mice per group were sacrificed and spleen cells analyzed by flow cytometry. (A) CD3⁺CD4⁺ T cells and CD3⁺CD8⁺ T cells were analyzed for their expression of CD62L and CD44 and categorized as naive cells (CD62L^hiCD44^-) or effector/memory cells (CD44⁺CD62L^- or CD44⁺CD62L⁺). (B-C) Longitudinal analysis of numbers and frequencies of (B) naive and effector/memory CD4⁺ T cells or (C) naive and effector/memory CD8⁺ cytotoxic T cells.