Table 7. Descriptive features of SNP72 and p53-mutated cancers by race and luminal subtype.
Race | Subtype | Age | Cancer death | SNP72 | Stage | Codon p53 | Consequence of mutation | Amino acid change |
---|---|---|---|---|---|---|---|---|
AA | Luminal | 61 | yes | Pro/Pro | late | 65 | nondisruptive | Arg > Lys |
AA | Luminal | 93 | yes | Pro/Pro | early | 191 | disruptive | Pro—> Ser |
AA | Luminal | 62 | no | Pro/Pro | early | 213 | disruptive | Arg>Stop |
AA | Luminal | 57 | no | Pro/Pro | early | 184 | disruptive | Asp—>Asn |
AA | Luminal | 62 | yes | Pro/Pro | late | 157 | nondisruptive | Val—>Ala |
AA | Luminal | 86 | no | Pro/Pro | late | 55 | nondisruptive | Thr > Ser |
AA | Luminal | 29 | yes | Pro/Pro | late | 136 | disruptive | Gln-> His |
AA | Luminal | 58 | no | Pro/Pro | early | 184 | disruptive | Asp—>Asn |
AA | Luminal | 36 | yes | Pro/Pro | late | 204 | disruptive | Glu—>Stop |
CA | Luminal | 84 | no | Pro/Pro | early | 69 | nondisruptive | Ala > Asp |
CA | Luminal | 50 | no | Pro/Pro | early | 213 | disruptive | Arg>Stop |
CA | Luminal | 66 | no | Pro/Pro | early | 237 | nondisruptive | Met—>Ile |
CA | Luminal | 67 | no | Pro/Pro | early | 213 | disruptive | Arg>Stop |