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A case of mucinous ACA of the ascending colon with two distinct but contiguous phenotypes: crypt cell/neuroendocrine carcinoma (A-C) and classical mucinous ACA (D-F), Immunohistochemical stains confirmed expression of Chromogranin in only the crypt cell/neuroendocrine component (B, E) and loss of SMAD4 expression in both regions of the tumor (C, F). Magnification: 200x.
