Table 2. SMAD4 mutations and mucinous differentiation.
SMAD4m (N = 28) | SMAD4wt (N = 57) | P_value | |||
---|---|---|---|---|---|
Mucinous | Yes | 17 (68%) | 9 (16%) | <0.00001 | |
differentiation | No/unknown | 11 (32%) | 48 (84%) | ||
MH2 domain (N = 12) | Other domains (N = 16) | ||||
Mucinous | Yes | 10 (83%) | 7 (44%) | 0.0338 | |
differentiation | No/unknown | 2 (17%) | 9 (56%) |