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. 2018 Dec 17;211(2):503–513. doi: 10.1534/genetics.118.301817

Figure 4.

Figure 4

The suppression by rph1∆ is not caused by the lack of Rph1 demethylase activity. (A) Deletion of Jhd1, Jhd2, or Gis1 does not suppress the MMS sensitivity of rad53∆. Strains: YBG022, YBG023, YBG034, YBG038, YBG130, and YBG469. (B) Deletion of Set2, Set1, or Dot1 does not prevent the suppression of the MMS of rad53∆ by rph1∆. Strains: YBG023, YBG034, YBG607, YBG608, and YBG609. (C) H3-K36R or H3K9R mutants cannot prevent the suppression of the MMS of rad53∆ by rph1∆. Strains: YBG047, YBG610, YBG101, YBG154, and YBG153. (D) The expression of a wild-type or demethylase-deficient Rph1 prevents the suppression by rph1∆. Either wild-type or mutated Rph1 versions were integrated in the genome of a rad53∆ rph1∆ strain. Strains: YBG022, YBG023, YBG034, YBG475, and YBG500.