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. 2018 Dec 17;211(2):503–513. doi: 10.1534/genetics.118.301817

Figure 5.

Figure 5

The deletion of NMD factors suppresses the rad53∆ sensitivity to MMS due to general hyperresistance to DNA damage. (A) Deletions of the NMD factors Nmd2, Xrn1, or Upf3 suppress the rad53∆ sensitivity to MMS. Strains: YJT72, YJT75, YBG071, YBG076, and YBG121. (B) nmd2∆, but not rxt2-Q102STOP, is hyperresistant to MMS, CPT, and UV. Strains: YJT72, YJT75, YBG455, YBG071, YBG456, and YBG245. CPT, camptothecin; NMD, nonsense-mediated mRNA decay; MMS, methyl methanesulfonate; UV, ultraviolet.