Figure 4.

Effects of annotation as TE, cytosine methylation, and chromosome region on mutation rates in 107 MA lines. Log-transformed mutation rates per site per generation are shown. Mutation rates for TE and non-TE positions are highlighted in blue and red, respectively. Mutation rates for AT positions as well as methylated and nonmethylated CG positions are indicated in square, triangle, and circle, respectively. Error bars indicate one SEM. Difference in mutation rates between chromosome arms and pericentromeric/centromeric regions among six classes was assessed by Student’s t-test and significance levels of these multiple tests were adjusted by sequential Bonferroni correction. NS indicates not significant and asterisks indicate P < 0.001 (***).