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The RM allele of RAD5 and BY allele of MKT1 increase mutation rate. The mutation rate of two allele replacement strains, the BY strain, and the RM strain are measured and compared. For each strain, 96 replicate measurements for mutation rate were performed. Bold lines show the mean. Boxes show the interquartile range. Statistical significance was tested using permutation t-test. Permutation P value <0.001 is shown as ***.
