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Loci underlying mutation rate variation, 4NQO sensitivity, and MMS sensitivity are overlapping. (A and B) The LOD scores for 4NQO (0.1 µg/ml) sensitivity and MMS (0.01%) sensitivity are plotted against the genetic map. The red line indicates a 5% FWER significance threshold (LOD = 3.62 for 4NQO and LOD = 3.61 for MMS).
