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. 2018 Dec 4;211(2):597–615. doi: 10.1534/genetics.118.301733

Figure 6.

Figure 6

UPR activation in yeast relative to wild-type rhodopsin. GFP expression is a reporter of UPR upregulation, while RFP is expressed constitutively to help correct for changes in global protein expression. WT: Wild-type human rhodopsin; Vector: yeast transformed with a plasmid not containing the rhodopsin gene; Strain: the yJW1200 strain not transformed with plasmid and grown in rich media; arRP: autosomal recessive retinitis pigmentosa. Data points represent results of nine individual colonies, each in a 600 μl culture, normalized to wild-type. Boxes extend from the 25th to 75th percentile, the line across the box represents the median value. Bars represent the min and max recorded values. * P < 0.05 vs. WT.