Table 2.

Relationship of Stool and Urine TFF3 to Gastrointestinal Symptoms and Stool Characteristics in Females with Irritable Bowel Syndrome

Symptomsa						Stool Characteristicsb
	Abdominal Pain	Constipation	Diarrhea	Intestinal Gas	Urgency	% Very Loose	% Loose	% Hard	% Very Hard	Number of Stools
Log of Stool TFF3
Simple correlation	0.05	−0.24*	0.22*	0.18	0.13	0.32**	0.19	−0.06	−0.07	0.22*
Partial correlationC	0.03	−0.26*	0.20	0.16	0.14	0.29**	0.18	−0.09	−0.11	0.15
Simple correlation, among participants not using hormone contraceptive	0.13	−0.22	0.17	0.19	0.18	0.22	0.16	−0.04	−0.10	0.07
Simple correlation, among hormone contraceptive users	−0.26	−0.35	0.31	0.08	0.03	0.55**	0.25	−0.28	−0.13	0.39*
Urine TFF3
Simple correlation	−0.06	0.01	−0.09	−0.01	−0.08	−0.13	0.01	−0.05	0.03	−0.22
Partial correlationC	0.01	−0.05	−0.20	−0.02	−0.22	−0.22	−0.10	−0.01	0.01	−0.10
Simple correlation, among participants not using hormone contraceptive	−0.04	−0.08	−0.06	0.03	0.05	−0.03	0.02	−0.06	−0.00	0.07
Simple correlation, among hormone contraceptive users	0.02	−0.06	−0.40*	−0.03	−0.39	−0.41*	−0.20	0.01	0.02	−0.20

Notes. TFF3 = Trefoil factor3. No Hormone Contraceptive (n = 45); Hormone Contraceptive (n = 24); Stool TFF3, n = 85.

^aSymptoms are measured as the % of days reported as moderate to severe on a 28-day diary.

^bStool characteristics are measured as percent of days with very loose stools, loose stools, etc.

^CPartial correlation controlling for hormone contraceptive. Pearson R was used.

^*p < 0.05

^**p < 0.01