. 2019 Feb 15;29(1):010707. doi: 10.11613/BM.2019.010707

Table 1. Variability within EliA^TM Calprotectin and Bühlmann fCAL Turbo method for measuring faecal calprotectin with respect to extraction method and stool consistency.

				Mean biases by BSS, %
Extraction method	FC concentration, mg/kg	P^†	Mean bias, %	Hard Stool	Normal Stool	Liquid Stool	P^‡
EliA^TM Calprotectin, N = 52*
Weighing method	125.0 (43.0 - 423.5)	0.484	0.1	- 8.9 (N = 7)	2.5 (N = 31)	- 0.8 (N = 14)	0.300
EliA Stool Extraction Kit extraction device	116.5 (36.0 - 407.5)	0.484	0.1	- 8.9 (N = 7)	2.5 (N = 31)	- 0.8 (N = 14)	0.300
Bühlmann fCAL® Turbo, N = 85*
Weighing method	140.0 (48.8 - 430.0)	< 0.001	33.3	34.3 (N = 14)	33.9 (N = 54)	33.3 (N = 17)	0.697
Calex® Cap “N” extraction device	167.0 (73.0 - 544.0)	< 0.001	33.3	34.3 (N = 14)	33.9 (N = 54)	33.3 (N = 17)	0.697
*2 samples out of 54 and 5 out of 90 were excluded as outliers. Faecal calprotectin (FC) concentration is presented as median (interquartile range).^†Comparison of medians was performed using the Wilcoxon test. Mean bias – mean of calculated biases (Bias = (FC_{extraction device} – FC_weighing) / FC_weighing x 100). BSS- Bristol stool scale classes (hard- BSS 1 and 2; normal- BSS 3, 4, 5; liquid- BSS 6, 7). ^‡Comparison of biases was performed using the Kruskal-Wallis test. P < 0.05 was considered statistically significant. The allowable bias was set at 22.6%.

Table 1. Variability within EliATM Calprotectin and Bühlmann fCAL Turbo method for measuring faecal calprotectin with respect to extraction method and stool consistency.